The Hedtrich Lab (BIH) is recruiting two Master students for NAM projects: Medium optimization for a gut-lung multi organ-on-chip system / CRISPR-based Gene Editing. The Lab is located in the just recently inaugurated research building Kaethe-Beutler-Haus on Berlin-Buch campus which is in close proximity to clinical departments, the MDC, and the FMP.
The Master Project should unravel the key components and medium formulation allowing for the co-culture of our intestinal and lung model. This investigation is crucial as each tissue requires very specific supplements which are not shared between different types of organs. Therefore, medium optimization currently represents one of the biggest struggles when developing multi-models.
The research project aims to develop topically applicable gene therapies for the treatment of monogenic diseases of human epithelia. We are looking for an enthusiastic scientist who will support the team with their expertise in genetic engineering. The focus will be on developing mRNA-based strategies to rescue disease-causing mutations. This project is part of a SPARK program, which has the goal to ultimately translate the findings from bench to bedside. Hence, interest in translational work at the forefront of science is a clear asset.