Publications

Scientific articles with participation of the Einstein Center 3R

  • Evaluating the Suitability of 3D Bioprinted Samples for Experimental Radiotherapy: A Pilot Study.
    Al-Zeer MA, Prehn F, Fiedler S, Lienert U, Krisch M, Berg J, Kurreck J, Hildebrandt G, Schültke, E.
    Int J Mol Sci. 2022 Sep 1;23(17):9951.
    PMID: 36077349  DOI: 10.3390/ijms23179951

 

  • Human alveolar progenitors generate dual lineage bronchioalveolar organoids.
    Hoffmann K, Obermayer B, Hönzke K, Fatykhova D, Demir Z, Löwa A, Alves LGT, Wyler E, Lopez-Rodriguez E, Mieth M, Baumgardt M, Hoppe J, Firsching TC, Tönnies M, Bauer TT, Eggeling S, Tran HL, Schneider P, Neudecker J, Rückert JC, Gruber AD, Ochs M, Landthaler M, Beule D, Suttorp N, Hippenstiel S, Hocke AC, Kessler M.
    Commun Biol. 2022 Aug 25;5(1):875.
    PMID: 36008580  DOI: 10.1038/s42003-022-03828-5

 

  • Introducing quality measures in an academic research consortium: Lessons and recommendation from implementing an ad hoc quality management system for organ model research.
    Hülsemann M, Wiebach J, Drude NI, Kniffert S, Behm L, Hönzke K, Baumgardt M, Hippenstiel S, Hocke AC, Dirnagl U, Tölch U.
    EMBO Rep. 2022 Aug 3;23(8):e55095.
    PMID: 35876564  DOI: 10.15252/embr.20225509

 

  • A pulmonologist's guide to perform and analyse cross-species single lung cell transcriptomics.
    Pennitz P, Kirsten H, Friedrich VD, Wyler E, Goekeri C, Obermayer B, Heinz GA, Mashreghi MF, Büttner M, Trimpert J, Landthaler M, Suttorp N, Hocke AC, Hippenstiel S, Tönnies M, Scholz M, Kuebler WM, Witzenrath M, Hoenzke K, Nouailles G.
    Eur Respir Rev. 2022 Jul 27;31(165):220056.
    PMID: 35896273  DOI: 10.1183/16000617.0056-2022

 

  • Hamster models of COVID-19 pneumonia reviewed: How human can they be?
    Gruber AD, Firsching TC, Trimpert J, Dietert K.
    Vet Pathol. 2022 Jul;59(4):528-545. 
    PMID: 34856819  DOI: 10.1177/03009858211057197

 

  • Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
    Hönzke K, Obermayer B, Mache C, Fathykova D, Kessler M, Dökel S, Wyler E, Baumgardt M, Löwa A, Hoffmann K, Graff P, Schulze J, Mieth M, Hellwig K, Demir Z, Biere B, Brunotte L, Mecate-Zambrano A, Bushe J, Dohmen M, Hinze C, Elezkurtaj S, Tönnies M, Bauer TT, Eggeling S, Tran HL, Schneider P, Neudecker J, Rückert JC, Schmidt-Ott KM, Busch J, Klauschen F, Horst D, Radbruch H, Radke J, Heppner F, Corman VM, Niemeyer D, Müller MA, Goffinet C, Mothes R, Pascual-Reguant A, Hauser AE, Beule D, Landthaler M, Ludwig S, Suttorp N, Witzenrath M, Gruber AD, Drosten C, Sander LE, Wolff T, Hippenstiel S, Hocke AC.
    Eur Respir J. 2022 Jun 21:2102725. 
    PMID: 35728978  DOI: 10.1183/13993003.02725-2021

 

  • The Rise of Three Rs Centres and Platforms in Europe.
    Neuhaus W, Reininger-Gutmann B, Rinner B, Plasenzotti R, Wilflingseder D, De Kock J, Vanhaecke T, Rogiers V, Jírová D, Kejlová K, Knudsen LE, Nielsen RN, Kleuser B, Kral V, Thöne-Reineke C, Hartung T, Pallocca G, Leist M, Hippenstiel S, Lang A, Retter I, Krämer S, Jedlicka P, Ameli K, Fritsche E, Tigges J, Buettner M, Bleich A, Baumgart N, Baumgart J, Meinhardt MW, Spanagel R, Chourbaji S, Kränzlin B, Seeger B, von Köckritz-Blickwede M, Sánchez-Morgado JM, Galligioni V, Ruiz-Pérez D, Movia D, Prina-Mello A, Ahluwalia A, Chiono V, Gutleb AC, Schmit M, van Golen B, van Weereld L, Kienhuis A, van Oort E, van der Valk J, Smith A, Roszak J, Stępnik M, Sobańska Z, Olsson IAS, Franco NH, Sevastre B, Kandarova H, Capdevila S, Johansson J, Cederroth CR, Sandström J, Ragan I, Bubalo N, Spielmann H.
    Altern Lab Anim. 2022 Mar;50(2):90-120.
    PMID: 35578444   DOI: 10.1177/02611929221099165

 

 

  • Animal experiments: EU is pushing to find substitutes fast.
    Hippenstiehl S, Thöne-Reineke C, Kurreck J.
    Nature. 2021 Dec;600(7887):37.
    PMID: 34848864  DOI: 10.1038/d41586-021-03539-7

 

  • Bioprinted Cancer Model of Neuroblastoma in a Renal Microenvironment as an Efficiently Applicable Drug Testing Platform.
    Wu D, Berg J, Arlt B, Röhrs V, Al-Zeer MA, Deubzer HE, Kurreck J.
    Int J Mol Sci. 2021 Dec 23;23(1):122.
    PMID: 35008547  DOI: 10.3390/ijms23010122

 

  • Bioprinted Multi-Cell Type Lung Model for the Study of Viral Inhibitors.
    Berg J, Weber Z, Fechler-Bitteti M, Hocke AC, Hippenstiel S, Elomaa L, Weinhart M, Kurreck J.
    Viruses. 2021 Aug 11;13(8):1590.
    PMID: 34452455  DOI: 10.3390/v13081590