This webinar explores the development and application of non-animal approaches in neuroscience, including using human neurons and organoids to better understand and treat Alzheimer’s disease and computational models of neuronal networks. The nervous system is the highest area of animal use for basic research in the UK and Europe with researchers often relying on animals to model the complexity of neuronal interactions and cognitive effects.
Speakers:
- Prof Ivan Nalvarte – Karolinska Institutet, Sweden: Brain organoids to study Alzheimer’s disease – a comparative approach.
- Prof Selina Wray – University College London, UK: Human neuronal models of Alzheimer’s disease for understanding disease mechanisms and developing novel therapies.
- Prof Dmitri Rusakov and Dr Leonid Savtchenko – University College London, UK: BRAINCELL, a computational platform to explore in silico realistic 3D brain cells and their interactions.
- A Q&A panel discussion will be facilitated by Dr Elvira Hukasova from The Swedish 3Rs Center.
Attendance will be certified.
Date and Time: 12.03.2025, 14:00-15:20 CET
More information and registration: here
About the webinar series:
In four sessions, the latest webinar series from The Togeth3R Consortium of European 3Rs centres will showcase non-animal approaches in the top four research fields of animal use in the UK and Europe:
Each webinar will feature three researchers presenting the scientific and 3Rs benefits of their approach, before a panel discussion on the latest developments and overcoming barriers to adoption. From organoids to microphysiological systems, using patient-derived samples or computational modelling, the series will showcase the efforts across Europe to deliver better science and replace animal models.